Uremia is a pathological condition where the body accumulates nitrogenous waste products of metabolism, including the urea.


The main cause is the accumulation of waste products in chronic renal failure. Kidneys filter the blood and produce the urine and this process allows cleansing the blood from potentially harmful waste substances.


The gradual increase of the concentration of nitrogen substance in blood leads to overall deterioration of health. The affected person does not feel well, loses weight and suffers from muscle weakness, nausea and vomiting. Final stages include disorders of consciousness, confusion, coma and death. The uremia is frequently accompanied with signs of pericarditis and polyneuropathy.


Blood tests can show us signs of increased serum amount of the nitrogen waste products. It is advisable to perform comprehensive kidney examination to evaluate their function.


We should treat the cause of acute or deteriorated chronic kidney failure, if it is of course possible. In principle, it is necessary to maintain a balanced intake and output of the fluids and to prevent dehydration. If we are unable to improve the kidney functions, dialysis is the only option.


Jiri Stefanek, MD  Author of texts: Jiri Stefanek, MD
 Contact: jiri.stefanek@seznam.cz
 Sources: basic text sources